Douglas James Veale Abstract Psoriatic arthritis (PsA) is the second most common inflammatory arthropathy, after rheumatoid arthritis diagnosis, in early arthritis clinics. Most patients have established psoriasis, often for years, prior to the onset of joint pain and swelling; in addition, associated features of nail disease, dactylitis, enthesitis, spondylitis or uveitis may be present. Psoriasis may [...]
Maja Bulatović Ćalasan, Oscar FC van den Bosch1 Marjonne CW Creemers, Martijn Custers, Antonius HM Heurkens, Jan Maarten van Woerkom and Nico M Wulffraat Introduction The aim of this study was to determine the prevalence of gastrointestinal and behavioural symptoms occurring before (anticipatory/associative) and after methotrexate (MTX) administration, termed MTX intolerance, in rheumatoid (RA) and psoriatic arthritis (PsA). Methods Methotrexate Intolerance Severity Score [...]
Laura C. Coates, William Tillett, David Chandler, Philip S. Helliwell, Eleanor Korendowych, Stuart Kyle, Iain B. McInnes, Susan Oliver, Anthony Ormerod, Catherine Smith, Deborah Symmons, Nicola Waldron and Neil J. McHugh on behalf of BSR Clinical Affairs Committee & Standards,Audit and Guidelines Working Group and the BHPR Background PsA is a chronic inflammatory arthropathy affecting up to 40% of patients with [...]
Published: Jun 13, 2013 | Updated: Jun 14, 2013 By Nancy Walsh, Staff Writer, MedPage Today Reviewed by Robert Jasmer, MD; Associate Clinical Professor of Medicine, University of California, San Francisco and Dorothy Caputo, MA, BSN, RN, Nurse Planner MADRID -- A year of treatment with apremilast, which targets inflammatory mediators, led to significant long-term reduction in disease activity among [...]
Twenty-Four–Week Efficacy and Safety Results of a Randomized, Placebo-Controlled Study Arthur Kavanaugh, Iain McInnes, Philip Mease, Gerald G. Krueger, Dafna Gladman, Juan Gomez-Reino, Kim Papp, Julie Zrubek, Surekha Mudivarthy, Michael Mack, Sudha Visvanathan, and Anna Beutler Methods. Adult patients with PsA who had at least 3 swollen and 3 tender joints and active psoriasis were randomly assigned to receive subcutaneous injections of placebo (n 113), golimumab 50 mg (n [...]
L Gossec, J S Smolen, C Gaujoux-Viala, Z Ash, H Marzo-Ortega, D van der Heijde, O FitzGerald, D Aletaha, P Balint, D Boumpas, J Braun, F C Breedveld, G Burmester, J D Cañete, M de Wit, H Dagfi nrud, K de Vlam, M Dougados, P Helliwell, A Kavanaugh, T K Kvien, R Landewé, T Luger, M Maccarone, D McGonagle, N McHugh, I B [...]