Nature Reviews Drug Discovery 7, 641 (2008).
Authors: Gil Y. Melmed, Stephan R. Targan, Uma Yasothan, Delphine Hanicq & Peter Kirkpatrick
In April 2008, certolizumab pegol (Cimzia; UCB), a tumour-necrosis factor blocker, was approved by the US FDA for the treatment of adult patients with moderate-to-severe Crohn’s disease who have not responded to conventional therapies.