Luqmani, R., Hennell, S., Estrach, C., Basher, D., Birrell, F., Bosworth, A., Burke, F., Callaghan, C., Candal-Couto, J., Fokke, C., Goodson, N., Homer, D., Jackman, J., Jeffreson, P., Oliver, S., Reed, M., Sanz, L., Stableford, Z., Taylor, P., Todd, N., Ver artigo completo
Nature Clinical Practice Endocrinology & Metabolism 4, 454 (2008). Author: Leonidas H Duntas Ver artigo completo
A Comissão Europeia (CE) aprovou a comercialização da versão de 50 miligramas de administração semanal do fármaco Enbrel (etanercept), da Wyeth, como alternativa à actual versão de 25 miligramas, administrada duas vezes por semana, para pacientes com psoríase em placas moderada a grave. Ver artigo completo
[Vasculitis syndromes: Edited by Phil Seo] Chung, Sharon A; Seo, Philip. Purpose of review: Due to the well known toxicities of cyclophosphamide, substantial interest exists in finding other therapies to treat primary systemic vasculitis. Biologic agents have been proposed as an alternative to cyclophosphamide for these disorders because of their recent success in treating other rheumatic [...]
Nature Clinical Practice Rheumatology 4, 597 (2008). Authors: Ingrid E Lundberg & Gustavo A Nader Ver artigo completo
A Comissão Europeia (CE) aprovou a comercialização do fármaco biológico Enbrel (etanercept), da Wyeth, para o tratamento da psoríase em placas grave em crianças. Este é o primeiro medicamento aprovado para esta indicação. A aprovação desta nova indicação já era esperada, visto vir no seguimento da recomendação positiva da Agência Europeia do Medicamento (EMEA), em Novembro [...]
Nature Reviews Drug Discovery 7, 641 (2008). Authors: Gil Y. Melmed, Stephan R. Targan, Uma Yasothan, Delphine Hanicq & Peter Kirkpatrick In April 2008, certolizumab pegol (Cimzia; UCB), a tumour-necrosis factor blocker, was approved by the US FDA for the treatment of adult patients with moderate-to-severe Crohn's disease who have not responded to conventional therapies. Ver [...]
Nature Clinical Practice Rheumatology 4, 565 (2008). Ver artigo completo
Lisa GM van Baarsen, Carina L Bos, Tineke CTM van der Pouw Kraan and Cornelis L Verweij Arthritis Research & Therapy - Latest articles Rheumatic diseases represent a diverse group of disorders. Most of these diseases are heterogeneous in nature, and show varying responsiveness to treatment. Since our understanding of the molecular complexity is incomplete and [...]
Arthritis / Rheumatology News From Medical News Today You come into a doctor's office with severe knee pain. The physician orders an MRI, which reveals substantial loss of cartilage-osteoarthritis, that is-in your knee joint. At this point, not much can be done beyond gulping down palliatives and trying to keep your weight off the joint. But [...]