Núcleo de Estudos de Doenças Auto-imunes

Sociedade Portuguesa de Medicina Interna
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Apresentação inicial de Colite Ulcerosa Com Manifestações Extra-intestinais Múltiplas

2016-07-13T15:53:00+01:00 2009-4-5|Categories: Casos Clínicos e Outros|

Ulcerative Colitis Initial Presentation With Multiple Extra-Intestinal Manifestations M. Raquel MARQUES, Susana OLIVEIRA, J.P. GORJÃO CLARA Resumo: As manifestações extraintestinais múltiplas estão presentes em 0.3 a 4.5% dos doentes com doença inflamatória intestinal (DII). Apresenta-se uma doente com 39 anos, internada por história com três meses de evolução de cervicalgia com incapacidade funcional, astenia, artrite tíbio-társica bilateral [...]

The 10-year follow-up data of the Euro-Lupus Nephritis Trial comparing low-dose and high dose intravenous cyclophosphamide

2016-07-13T12:54:40+01:00 2009-1-20|Categories: Lúpus Sistémico Eritematoso|

F A Houssiau, C Vasconcelos, D D’Cruz, G D Sebastiani, E de Ramon Garrido, M G Danieli, D Abramovicz, D Blockmans, A Cauli, H Direskeneli, M Galeazzi, A Gu¨l, Y Levy, P Petera, R Popovic, R Petrovic, R A Sinico, R Cattaneo, J Font, G Depresseux, J-P Cosyns, R Cervera ABSTRACT Objective: To update the follow-up of the Euro-Lupus Nephritis Trial (ELNT), a randomised prospective trial comparing low-dose (LD) and high-dose (HD) intravenous (IV) cyclophosphamide (CY) followed by [...]

Saber viver com a artrite reumatoide ou a espondilite anquilosante na gravidez

2016-07-09T09:40:57+01:00 2009-1-18|Categories: Artigos Originais e de Revisão|Tags: , , , , , , , |

Knowing how to live with rheumathoid arthritis or ankylosing spondilytis during pregnancy João Araújo Correia* Resumo A artrite reumatóide (AR) e a espondilite anquilosante (EA) são doenças que atingem mulheres jovens que vêm a manifestar o seu desejo de engravidar. O médico deve estar preparado para responder a todas as perguntas, realçando as vantagens de uma [...]

NICE guidelines on anti-tumor necrosis factor therapy for RA

2016-07-13T20:19:12+01:00 2009-1-5|Categories: Arquivo|

David L Scott* and Sophia Steer The UK National Institute for Health and Clinical Excellence (NICE) utilizes the available evidence to provide guidance on the efficacy and cost-effectiveness of existing health technologies. NICE advisors decide that a technology is of value to society when its cost falls beneath a certain threshold—conventionally under £30,000 (approximately $50,000) per [...]

Etanercept for patients with RA: more is not always better

2016-07-13T09:09:25+01:00 2009-1-5|Categories: Artrite Reumatóide|

Joel M Kremer Abstract Weinblatt and colleagues have studied the efficacy and safety of etanercept 50 mg twice weekly in comparison with etanercept 50 mg once weekly in patients with longstanding rheumatoid arthritis. The study failed to demonstrate any clinically meaningful or statistically significant benefit of the use of the twice weekly dosage. There was also [...]

MESENTERITE ESCLEROSANTE

2016-10-16T12:02:17+01:00 2009-1-4|Categories: Casos Clínicos e Outros|

SCLEROSING MESENTERITIS Margarida FERREIRA, Amílcar SILVA, Manuela MERUJE, Diogo CABRITA, Ana FIGUEIREDO Resumo: A Mesenterite Esclerosante é uma doença rara, idiopática. Representa o estádio final de progressão das doenças inflamatórias crónicas do mesentério intestinal, com predomínio do componente fibrótico. As manifestações clínicas são variadas e inespecíficas. O diagnóstico, que exige elevado grau de suspeição, pode ser presumido [...]

Networking in Europe for special centres of excellence for autoimmune diseases

2016-07-13T12:57:12+01:00 2009-1-1|Categories: Lúpus Sistémico Eritematoso|Tags: , , , |

C Vasconcelos and R Cervera The studies developed by the European Working Party on Systemic Lupus Erythematosus and the European Forum on Antiphospholipid Antibodies stress the importance of the creation of international networks devoted to the study of autoimmune diseases and the need for centres of excellence in the management of these conditions. This article analyses the importance of such [...]

European consensus statement on the terminology used in the management of lupus glomerulonephritis

2016-07-13T12:55:31+01:00 2009-1-1|Categories: Lúpus Sistémico Eritematoso|Tags: , , |

C Gordon, D Jayne, C Pusey, D Adu, Z Amoura, M Aringer, J Ballerin, R Cervera, J Calvo-Alén, C Chizzolini, JM Dayer, A Doria, F Ferrario, J Floege, L Guillevin, M Haubitz, F Hiepe, F Houssiau, P Lesavre, L Lightstone, PL Meroni, O Meyer, B Moulin, KO’Reilly, M Praga, H Schulze-Koops, RA Sinico, KGC Smith, A Tincani, C Vasconcelos and [...]

Síndromes reno-pulmonares associadas a anticorpo anticitoplasma do neutrófilo

2016-10-16T12:02:17+01:00 2009-1-1|Categories: Artigos Originais e de Revisão|Tags: , , , , , , , , |

Pulmonary-renal syndrome associated with antineutrophil cytoplasmic antibodies Irina Didenko*, Sara Correia**, Fatima Ferreira***, Vitor Augusto§ Resumo A síndrome reno-pulmonar e caracterizada pela associação de hemorragia alveolar e glomerulonefrite rapidamente progressiva (GNRP), no contexto de doenças graves, frequentemente associadas a positividade serica para o anticorpo anticitoplasma do neutrófilo (ANCA). A granulomatose de Wegener (WG), a poliangeite microscópica [...]

Association between the interleukin 23 receptor and ankylosing spondylitis is confirmed by a new UK case–control study and meta-analysis of published series

2016-10-16T12:02:17+01:00 2008-12-10|Categories: Espondilite Anquilosante|Tags: , , , , |

Tugce Karaderi, David Harvey, Claire Farrar, Louise H. Appleton, Millicent A. Stone,Roger D. Sturrock, Matthew A. Brown, Paul Wordsworth and Jennifer J. Pointon Correspondence to: Jennifer J. Pointon, Oxford University Institute of Musculoskeletal Science, Botnar Research Centre, Nuffield Orthopaedic Centre, Windmill Road, Headington, Oxford OX3 7LD, UK. E-mail: jennyp@well.ox.ac.uk Received August 29, 2008. Revision received December 10, 2008. Abstract Objectives. It has been shown previously that IL-23R variants are associated [...]