Publicações

B lymphocyte-typing for prediction of clinical response to rituximab

marco.marques 2016-07-09T08:40:43+01:00 2012-12-1|Categories: Divulgação|Tags: artrite reumatóide, rituximab|

Introduction: The prediction of therapeutic response to rituximab in rheumatoid arthritis is desirable. We evaluated whether analysis of B lymphocyte subsets by flow cytometry would be useful to identify non-responders to rituximab ahead of time. Methods: Fifty-two patients with active rheumatoid arthritis despite therapy with TNF-inhibitors were included in the national rituximab registry. DAS28 was determined before and [...]

Inflammation associated anemia and ferritin as disease markers in SLE

marco.marques 2016-07-09T08:39:28+01:00 2012-12-1|Categories: Divulgação|Tags: anemia, les, lúpus sistémico eritematoso, sle|

Introduction: In a recent screening to detect biomarkers in systemic lupus erythematosus (SLE), expression of the iron storage protein, ferritin, was increased. Given that proteins that regulate the storage, transfer and release of iron play an important role in inflammation, this study aims to determine the serum and urine levels of ferritin and of the iron transfer protein, transferrin, [...]

Can Flare Be Predicted in DMARD Treated RA Patients in Remission, and Is It Important?

marco.marques 2016-07-13T08:48:48+01:00 2012-8-29|Categories: Artrite Reumatóide|

Abstract Objectives The treatment target for patients with rheumatoid arthritis (RA) is remission. Imaging techniques and remission criteria may identify patients at risk of flare and associated consequences. This study aimed to determine the clinical, functional and imaging associations of disease flare in patients with RA in remission and any effect on long-term outcomes. Methods RA patients in [...]

LPN Days Rheumatology Salary in Baton Rouge, LA

marco.marques 2016-07-09T08:47:14+01:00 2012-8-29|Categories: Divulgação|

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House Bill 6218 would create interdepartmental autoimmune disease coordinating committee

marco.marques 2016-10-16T12:02:14+01:00 2012-8-21|Categories: Divulgação|

Autoimmune disease patients received a win recently when U.S. Rep. Ann Marie Buerkle (R-NY) introduced House Bill 6218 to Congress. The bill would create an interdepartmental autoimmune disease coordinating committee. The governmental agency committee would include the Assistant Secretary of Health, the Commissioner of Food and Drugs and the Director of the National Institutes of Health [...]

Early systemic sclerosis: short-term disease evolution and factors predicting the development of new manifestations of organ involvement

marco.marques 2016-10-16T12:02:14+01:00 2012-8-17|Categories: Divulgação|Tags: Raynaud, SSc, UCTD|

Introduction. We investigated early Systemic Sclerosis (SSc) (i.e. Raynaud’s phenomenon with SSc marker autoantibodies and/or typical capillaroscopic findings and no manifestations other than puffy fingers or arthritis) versus Undifferentiated Connective Tissue Disease (UCTD) to identify predictors of short-term disease evolution. Methods. Thirty-nine early SSc and 37 UCTD patients were investigated. At baseline, all patients underwent clinical evaluation, B-mode echocardiography, lung [...]

Multibiomarker Disease Activity Test Complements Clinical Assessment in Rheumatoid Arthritis CME

marco.marques 2016-07-19T21:25:32+01:00 2012-7-24|Categories: Artrite Reumatóide|

News Author: Janis C. Kelly CME Author: Désirée Lie, MD, MSEd Faculty and Disclosures CME Released: 07/16/2012; Valid for credit through 07/16/2013 Consulte artigo

The effect of smoking or alcohol consumption on markers of systemic inflammation, immunoglobulin levels and immune response following pneumococcal vaccination in patients with arthritis

marco.marques 2016-07-13T08:50:04+01:00 2012-7-24|Categories: Artrite Reumatóide|

Carmen Roseman (carmen.roseman@skane.se}) Lennart Truedsson (lennart.truedsson@skane.se}) Meliha C Kapetanovic (meliha.c_kapetanovic@med.lu.se}) Abstract Introduction To study influence of cigarette smoking and alcohol consumption on immune response to heptavalent pneumococcal conjugate vaccine, immunoglobulin levels (Ig) and markers of systemic inflammation in patients with rheumatoid arthritis (RA) or spondylarthropathy (SpA). Methods In total, 505 patients were vaccinated. Six prespecified groups were enrolled: RA on MTX treatment [...]

Diagnosis and treatment of lupus nephritis

marco.marques 2016-10-16T12:02:14+01:00 2012-1-1|Categories: Lúpus Sistémico Eritematoso|

Consensus document from the systemic auto-immune disease group (GEAS) of the Spanish Society of Internal Medicine (SEMI) and the Spanish Society of Nephrology (S.E.N.) Guillermo Ruiz-Irastorza, Gerard Espinosa, Miguel A. Frutos, Juan Jiménez-Alonso, Manuel Praga, Lucio Pallarés, Francisco Rivera, Ángel Robles-Marhuenda, Alfons Segarra, Carlos Quereda Lupus nephritis affects over half of all patients with systemic lupus erythematosus (SLE). This condition [...]

The Pathogenesis of Rheumatoid Arthritis

marco.marques 2016-10-16T12:02:14+01:00 2011-12-8|Categories: Artrite Reumatóide|

Rheumatoid arthritis is a common autoimmune disease that is associated with progressive disability, systemic complications, early death, and socioeconomic costs.1 The cause of rheumatoid arthritis is unknown, and the prognosis is guarded. However, advances in understanding the pathogenesis of the disease have fostered the development of new therapeutics, with improved outcomes. The current treatment strategy, which reflects this progress, is to initiate [...]

Núcleo de Estudos de Doenças Auto-imunes

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